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2 edition of Vanilmandelic acid and catecholamine determinations found in the catalog.

Vanilmandelic acid and catecholamine determinations

Thomas C. Stewart

Vanilmandelic acid and catecholamine determinations

by Thomas C. Stewart

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  • 25 Currently reading

Published by American Society of Clinical Pathologists in Chicago .
Written in English


Edition Notes

Statement[by] Thomas C. Stewart [and] James A. Freeman.
ContributionsFreeman, James A.
ID Numbers
Open LibraryOL13831596M

  I claim 1. In a method for determining the content of vanilmandelic acid in urine by preparing a concentrate of vanilmandelic acid from the urine, diazotizing the vanilmandelic acid contained in the concentrate, extracting the diazotized vanilmandelic acid with an organic solvent and determining the optical density of the extract, the improvement which comprises using cyclohexanone . Excretion of Adrenaline, Noradrenaline, Vanilmandelic Acid and Metanephrines in 64 Patients with Pheochromocytoma Article in Journal of Internal Medicine (2) - April with 16 Reads.

An improved gas chromatographic determination of urinary catecholamine metabolites GARRY F TAYLOR, THACH DUONG AND NORRIS G CARTER SUMMARY We describe an improved gas chromatographic method for the determination of 3­ methoxyhydroxymandelic acid (vanilmandelic acid), 3-methoxyhydroxyphenyacetic-acid found that previously reported. CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): L-Dopa and its major metabolites were separated from daily h urines from patients with Parkinson’s disease, who were being treated with in. creasing doses of the drug, up to 4 g per day. An aliquot of each sample was passed through three different ion-exchange columns.

A Certified Spiking Solution ® of major catecholamine metabolites 5-Hydroxyindoleacetic acid (5-HIAA), Homovanillic acid (HVA), and (±)-Vanilmandelic acid (VMA).This multi-component mix is suitable for use in preparation of linearity standards, calibrators, or controls as well as for other critical quantitative applications such as internal proficiency testing or for OEM use in. The urinary excretion of catecholamines in 13 close rela tives of two distantly related patients with congenital neuro blastoma was investigated. One of these relatives was a child with already known ganglioneuroblastoma. The cate cholamines noradrenaline and dopamine were determined. Vanilmandelic acid and homovanillic acid also were deter.


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Vanilmandelic acid and catecholamine determinations by Thomas C. Stewart Download PDF EPUB FB2

Vanilmandelic acid & catecholamine determinations. Chicago: American Society of Clinical Pathologists, (OCoLC) Document Type: Book: All Authors / Contributors: Thomas C Stewart; James A Freeman.

Spectrum of catechol amine biochemistry in patients with neuroblastoma. Acido vanilmandelico – Wikipedia. Urinary vanilmandelic acid VMA excretion in children: O-Methylation, the principal route of metabolism of epinephrine in man.

Chemical thermogenesis in newborn infants: Catecholamine metabolite excretion of infants with heart failure. Vanilmandelic acid & catecholamine determinations. Chicago: American Society of Clinical Pathologists. MLA Citation. Stewart, Thomas C. and Freeman, James A. Vanilmandelic acid & catecholamine determinations / Thomas C.

Stewart, James A. Freeman American Society of Clinical Pathologists Chicago Australian/Harvard Citation. Determination of urinary 3-methoxyhydroxymandelic acid in man. National Center for Biotechnology InformationU. Urinary vanilmandelic acid VMA excretion in children: N Engl J Med.

Excretion of catecholamine catabolites by normal children. Urinary catecholamine excretion by. Urinary excretion of norepinephrine, epinephrine and 3-methoxyhydroxymandelic acid by children with neuroblastoma. N Engl J Med. Urinary vanilmandelic acid VMA excretion in children: Abstract 4-Hydroxymethoxymandelic acid HMMA concentrations in aqueous humour, urine, and serum were simultaneously estimated to determine if these levels were raised in cases of retinoblastoma.

Vanillylmandelic acid (VMA) and other catecholamine metabolites (homovanillic acid [HVA] and dopamine) are typically elevated in patients with catecholamine-secreting tumors (eg, neuroblastoma, pheochromocytoma, and other neural crest tumors).

Vanillylmandelic acid (VMA) is produced in the liver and is a major product of norepinephrine and epinephrine metabolism excreted in the urine. Therefore VMA is a poor diagnostic marker for pheochromocytoma given that very little is derived from catecholamine and metanephrines.

Homovanillic acid (HVA), in contrast. Two separate controlled experiments in man measured the excretion of epinephrine, norepinephrine, vanilmandelic acid (VMA) and total metanephrines following lysergic acid diethylamide (LSD), comparisons being made with an injection of a similar dose of epinephrine in the one instance and with a no-treament period in the other.

LSD (2 mcg/kg) produced insignificant changes in urinary Cited by: 8. Limite şi interferenţe. Un procent de % din pacienţii cu neuroblastom nu prezintă excreţie urinară crescută de acid ştia prezintă alte anomalii de laborator, cum ar fi: valori crescute de metanefrine, acid homovanilic sau dopamina pentru diagnosticul neuroblastomului se recomandă determinarea simultană de acid vanilmandelic şi acid homovanilic.

Elevated values of homovanillic acid (HVA), vanillylmandelic acid (VMA), and other catecholamine metabolites (eg, dopamine) may be suggestive of the presence of a catecholamine-secreting tumor (eg, neuroblastoma, pheochromocytoma, or other neural crest tumors).

Urinary catecholamines (DA, NE, E) and their main metabolites (HVA, DOPAC, MHPG) were analyzed both as free and conjugates in eight children diagnosed as autistic according to DSM-III criteria and eight normal children.

Significant differences appeared for the urinary excretion of both DA and NE and their respective metabolites: Autistic children showed low DA, high HVA, high NE, low Cited by: VMA: Vanillylmandelic acid (VMA) and other catecholamine metabolites (homovanillic acid [HVA] and dopamine) are typically elevated in patients with catecholamine-secreting tumors (eg, neuroblastoma, pheochromocytoma, and other neural crest tumors).

VMA and HVA levels may also be useful in monitoring patients who have been treated as a result of 1 of the above-mentioned tumors. Literature References: Catecholamine metabolite. Urine levels elevated in various pathologies. Misnamed vanillinemandelic acid and vanillylmandelic from. Vanillyl mandelic acid (VMA) is an end-stage metabolite of the catecholamines epinephrine and norepinephrine.

It is produced via intermediary metabolites. It is produced via intermediary metabolites. VMA is found in the urine, along with other catecholamine metabolites, including homovanillic acid (HVA), metanephrine, and nation geometry:.

Auditory sensory gating and catecholamine metabolism in schizophrenic and normal subjects. Psychiatry Research44 (1), DOI: /(92)C. Mario A. Zilli. Simple and fast chromatographic method for the simultaneous determination of vanillylmandelic acid and homovanillic acid in human by: Vanillylmandelic acid is one of the products of the catabolism of catecholamines (epinephrine, norepinephrine and dopamine).

High levels of vanillylmandelic acid can indicate an adrenal gland tumor (pheochromocytoma) or another type of tumor that produces catecholamines. Vanillylmandelic acid (VMA) is produced in the liver and is a major product of norepinephrine and epinephrine metabolism excreted in the urine.

Therefore VMA is a poor diagnostic marker for pheochromocytoma given that very little is derived from catecholamine and metanephrines. Vanillylmandelic acid (VMA) is final metabolic product of catecholamine hormone epinephrine in human body [1] and a well-established biomarker of various diseases, which are linked to altered.

A rapid method is described for the determination of urinary free catecholamines by HPLC with electrochemical detection. Optimised and equilibrium assay conditions are assessed for sample preparation, separation and detection.

Catecholamine stability is maintained during the assay procedure by the addition of a combined reducing by: Vanillylmandelic acid (VMA) is one of the breakdown products (metabolites) of epinephrine (adrenaline) and norepinephrine. Epinephrine and norepinephrine belong to a group of similar hormones called catecholamines.

This test measures the amount of VMA that is passed into the urine, typically over a hour period. In the group of children with neuroblastoma without evidence of disease, dopa and catecholamine levels were within the range observed in the controls.

Total urinary catecholamines, homovanillic acid (HVA) and/or vanilmandelic acid (MVA) were elevated in 11 of Cited by: VH: Elevated values of homovanillic acid (HVA), vanillylmandelic acid (VMA), and other catecholamine metabolites (eg, dopamine) may be suggestive of the presence of a catecholamine-secreting tumor (eg, neuroblastoma, pheochromocytoma, or other neural crest tumors).

HVA and VMA levels may also be useful in monitoring patients who have been treated as a result of the above-mentioned tumors./ High-performance liquid chromatographic determination of catecholamine metabolites and 5-hydroxyindoleacetic acid in human urine using a mixed-mode column and an eight-channel electrode electrochemical detector.

In: Journal of Chromatography B: Biomedical Sciences and Applications. ; Vol.No. 1. pp. Cited by: